Wie hängen die Aktivität von Neuronen, das Explorationsverhalten und die Parkinson- Erkrankung zusammen? Forschergruppen um die NGFN-Wissenschaftler Professor Birgit Liss in Ulm und Professor Jochen Roeper in Frankfurt haben nun herausgefunden, dass ein spezielles Protein, ein so genannter K-ATP Ionenkanal, entscheidend für die Aktivitätsmuster bestimmter Dopamin-produzierender Nervenzellen ist - und damit wichtig für die Pathophysiologie des Morbus Parkinson, aber auch für das Explorationsverhalten. Diese neuen Erkenntnisse der unter anderem über das Nationale Genomforschungsnetz (NGFN), den Frankfurter Sonderforschungsbereich "Redox Regulation" (SFB815), den Ulmer SFB 497 und die Alfried Krupp-Stiftung geförderten Arbeit wurden nun im renommierten Fachjournal Nature Neuroscience veröffentlicht.
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