Bei einem bestimmten Typ von Medulloblastomen - gefährlichen Hirntumoren bei Kindern - sind die Ursachen in 40 Prozent aller Fälle angeboren. Das zeigt eine aktuelle Genomanalyse von Wissenschaftlern des Hopp-Kindertumorzentrums (KiTZ), des Europäischen Laboratoriums für Molekularbiologie (EMBL) und zahlreichen Kollegen weltweit, die jetzt im Fachmagazin Nature veröffentlicht wurde. Eine besondere Rolle spielt dabei ein genetischer Defekt, der bei 15 Prozent dieser Kinder auftritt und dazu führt, dass die Produktion und der Abbau von Eiweißen aus dem Gleichgewicht geraten. Die Wissenschaftler vermuten jetzt, dass Störungen im Proteinhaushalt eine bislang unterschätzte Ursache auch bei anderen Tumorarten sein könnten.
Das "Hopp-Kindertumorzentrum Heidelberg" (KiTZ)
Das "Hopp-Kindertumorzentrum Heidelberg" (KiTZ)
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Lvonqflcbghyzupjmks:
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Lvonqflcbghyzupjmks:
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