Statt Tumorlokalisation ist molekulargenetische Aufklärung von Tumoren maßgeblich für onkologische Therapien / Larotrectinib ist der erste Wirkstoff mit tumorunabhängiger Indikation in der EU für die Behandlung von Erwachsenen und pädiatrischen Patienten mit soliden Tumoren mit einer NTRK(1)-Genfusion / Voraussetzung für den Einsatz der Therapie ist der Nachweis einer NTRK-Genfusion / Larotrectinib zeigte hohe Ansprechraten, eine langanhaltende Wirkung und eine gute Verträglichkeit bei Erwachsenen und Kindern mit TRK(2)-Fusionstumoren
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