Neue post-hoc Analysen aus der vorab spezifizierten Analyse FIDELITY, welche die Studien FIDELIO-DKD und FIGARO-DKD gepoolt untersuchte, liefert Einblicke zur Wirkung von Finerenon auf renale und kardiovaskuläre Ergebnisse bei Verwendung von Glucagon-ähnlichen Peptid-1-Rezeptoragonisten (GLP-1RA) zu Studienbeginn, sowie nach HbA1c-Variabilität und Dauer der Diabeteserkrankung bei Patienten mit chronischer Nierenerkrankung (CKD) und Typ-2-Diabetes (T2D)
Eine exploratorische Subgruppenanalyse von FIDELITY ermöglicht weitere Einblicke in die Wirksamkeit und Sicherheit von Finerenon bei CKD- und T2D-Patienten mit Adipositas, definiert durch ein wesentlich erhöhtes Taillen-Hüft-Verhältnis
Das Design der Phase-II-Studie CONFIDENCE wird vorgestellt, welche die gleichzeitig initiierte Kombinationstherapie mit Finerenon und einem SGLT2-Inhibitor bei Patienten mit CKD und
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Wxboclpxl 63, 7214; 19:89 – 0:33uj (CIIE)
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Reocmpotv 77, 1511; 56:36 – 8:98kw (VUYH)
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Kdxdgtnlx 95, 7543; 3:27 – 3:18za (JKIG)
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Yyyjmltnvktlenmbiw Esirowro
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