.
- Xarelto® in der vaskulären Dosierung plus ASS 100 mg senkt das kombinierte Risiko einer Extremitätenischämie und schwerer kardiovaskulärer Ereignisse bei Patienten mit symptomatischer peripherer arterieller Verschlusskrankheit nach Revaskularisierung signifikant
- Bisher einzige Studie, in der die Wirksamkeit einer Kombination aus Gerinnungshemmung und Plättchenhemmung bei dieser stark gefährdeten Patientengruppe, für die es wenige Behandlungsoptionen gibt, gezeigt wurde
- Risiko einer akuten Extremitätenischämie im Vergleich zu ASS allein signifikant um – 33 % – vermindert
- Kein signifikanter Anstieg der Rate an schweren Blutungen nach der TIMI-Definition – dem Hauptkriterium zur Beurteilung der Sicherheit in dieser Studie
Die klinische Phase-III-Studie VOYAGER PAD
- Xarelto® in der vaskulären Dosierung plus ASS 100 mg senkt das kombinierte Risiko einer Extremitätenischämie und schwerer kardiovaskulärer Ereignisse bei Patienten mit symptomatischer peripherer arterieller Verschlusskrankheit nach Revaskularisierung signifikant
- Bisher einzige Studie, in der die Wirksamkeit einer Kombination aus Gerinnungshemmung und Plättchenhemmung bei dieser stark gefährdeten Patientengruppe, für die es wenige Behandlungsoptionen gibt, gezeigt wurde
- Risiko einer akuten Extremitätenischämie im Vergleich zu ASS allein signifikant um – 33 % – vermindert
- Kein signifikanter Anstieg der Rate an schweren Blutungen nach der TIMI-Definition – dem Hauptkriterium zur Beurteilung der Sicherheit in dieser Studie
Die klinische Phase-III-Studie VOYAGER PAD
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